Mumbai

August 13, 2025

On August 13th, 2025, C-DAC Pune signed a Memorandum of Understanding (MoU) with the Sri Sathya Sai Sanjeevani Research Foundation (SSSSRF), Bengaluru, at Kharghar, Navi Mumbai, Maharashtra. The MoU was signed by Shri. Sanjay Wandhekar, Centre Head, C-DAC Pune, and Dr. C. Sreenivas, Chairman, SSSSRF, in the presence of Shri. Sunil Gavaskar; Dr. Uddhavesh Sonavane, Programme Director and Scientist G, HPC Medical and Bioinformatics Applications Group, C-DAC Pune; Dr. Sanjay Gupta, Principal Investigator, Tata Memorial Centre - ACTREC, Mumbai; Shri. Vinod Jani, Scientist F, C-DAC Pune; Shri. Sandeep Malviya, Scientist F, C-DAC Pune; Ms. Ruma Banerjee, Scientist F, C-DAC Pune; and senior representatives from SSSSRF.

The MoU sets a framework for comprehensive collaboration in the areas of computational biology, advanced research, and training for societal impact. It emphasises joint efforts in high-throughput computational analysis of massive datasets generated from genome sequencing, genome methylation sequencing, and RNA sequencing, enabling transcriptome-wide expression dynamics of biological samples. The collaboration will also focus on advanced training in next-generation sequencing (NGS), empowering researchers and students to master sequencing workflows, understand data quality, interpret diverse file formats, apply QC tools, and explore bioinformatics-driven automated solutions.

Another key focus will be the creation of an integrated digital platform that links clinical data with research by streamlining patient records and bio-specimen tracking, thereby enabling real-time monitoring and research analytics. The partnership also aims to develop advanced algorithms for extracting patterns, correlations, and predictive insights from large-scale metadata, enhancing integration, classification, and decision-making in biological and clinical research.

In addition, molecular simulation and modelling studies will be pursued to unravel mechanisms underlying folic acid supplementation, one-carbon metabolism, vitamin B12-related pathways, and the effects of human exposure to heavy metals. These efforts hold the potential to provide critical insights into nutritional biology and public health.

This MoU is poised to greatly strengthen collaborative research and academic engagement, driving innovation at the interface of healthcare, life sciences, and high-performance computing, while serving the broader interest of mankind, the nation, and society.